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NLRP3
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8:53
YouTube
ilovepathology
Pyroptosis | Cell Death Mechanism Explained | Pathology Made Simple
Chapters: 00:00 – Introduction: What is Pyroptosis? (Definition & Key Features) 01:21 – Pathways of Pyroptosis (Canonical vs Non-Canonical) 02:35 – Canonical Pathway: NLRP3 Inflammasome, Caspase-1, IL-1β & Gasdermin D 04:48 – Non-Canonical Pathway: LPS Activation of Caspase-4/5 → Gasdermin D Cleavage 05:50 – Roles of Pyroptosis ...
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