Magnesium glycinate is well-known for its calming effects on the nervous system and one of the leading mineral supplements to support sleep. But for a rare few, supplementing magnesium glycinate actually keeps them awake at night … likely from the amino acid glycine which the magnesium is bound to, to create magnesium glycinate, causing a stimulatory experience, rather than inhibitory … which is more common with glycine. If this is you, it could be worth trying a magnesium threonate supplement.