99 BOMBS?! | The Binding Of Isaac Afterbirth Daily Challenge #4
45:41
99 BOMBS?! | The Binding Of Isaac Afterbirth Daily Challenge #4
181.4K viewsAug 5, 2017
YouTubeYuB
the isaac BACKWARDS challenge
45:06
the isaac BACKWARDS challenge
529K viewsApr 16, 2020
YouTubeYuB
PEE YOURSELF CHALLENGE | The Binding Of Isaac Afterbirth Gameplay [Nintendo Switch]
17:46
PEE YOURSELF CHALLENGE | The Binding Of Isaac Afterbirth Gamep…
355.1K viewsJul 6, 2017
YouTubeYuB
YOU EAT ALL MY BEANS ISAAC?!
41:05
YOU EAT ALL MY BEANS ISAAC?!
99.6K viewsOct 4, 2019
YouTubeYuB
EPIC RUN AS THE FORGOTTEN! (Binding Of Isaac)
32:39
EPIC RUN AS THE FORGOTTEN! (Binding Of Isaac)
1.5M viewsFeb 27, 2019
YouTubeYuB
we did it boys (head trauma challenge)
35:56
we did it boys (head trauma challenge)
365.3K viewsApr 9, 2019
YouTubeYuB
isaac perfect accuracy challenge (this sucks)
38:45
isaac perfect accuracy challenge (this sucks)
321.9K viewsJul 6, 2020
YouTubeYuB
19:33
the most CURSED isaac challenge
207.2K viewsApr 17, 2019
YouTubeYuB
36:23
the isaac purist challenge is not that easy
193.6K viewsNov 23, 2019
YouTubeYuB
23:40
hey isaac, ya want flies with that?
180.3K viewsJun 6, 2019
YouTubeYuB
18:11
the most annoying isaac challenge ever
162.3K viewsDec 28, 2020
YouTubeYuB
30:05
isaac big brain challenge
136.8K viewsNov 5, 2020
YouTubeYuB
1:00:06
isaac finds his long lost family! (adorable)
918.1K viewsMar 23, 2019
YouTubeYuB
38:24
UNLOCKING THE FORGOTTEN! (Binding Of Isaac)
1.8M viewsFeb 14, 2019
YouTubeYuB
57:57
trying terrible isaac challenges (and hating it)
119.4K viewsMay 5, 2020
YouTubeYuB
44:08
BUMBO IS INSANE (Binding Of Isaac)
667.4K viewsJan 18, 2019
YouTubeYuB
54:15
these isaac trinkets are OVERPOWERED DUDE
161.8K viewsOct 30, 2022
YouTubeYuB
38:35
ok but apollyon is kinda great (binding of isaac)
784.1K viewsMar 6, 2019
YouTubeYuB
11:46
HEAD TRAUMA CHALLENGE [Attempt #1] The Binding Of Isaac …
65.3K viewsAug 16, 2017
YouTubeYuB
33:04
APOLLYON VS ULTRA GREEDIER (binding of isaac)
739.1K viewsJun 25, 2019
YouTubeYuB
30:10
LASER MOUTH DEMON BABY | The Binding Of Isaac Afterbirth Daily C…
155.8K viewsJul 11, 2017
YouTubeYuB
20:22
isaac gets killed by poop (depressing)
99.2K viewsDec 8, 2020
YouTubeYuB
22:24
isaac challenge with no tears
210.1K viewsMay 5, 2019
YouTubeYuB
44:08
SMALLEST ISAAC EVER | The Binding Of Isaac Afterbirth Gamep…
279.5K viewsNov 28, 2017
YouTubeYuB
35:43
TINY ISAAC VS THE LAMB
674.8K viewsFeb 1, 2019
YouTubeYuB
32:55
MOST STRESSFUL ISAAC RUN EVER
198K viewsJan 24, 2019
YouTubeYuB
30:14
try not to edit challenge #1
87K viewsApr 25, 2023
YouTubeYuB
37:18
I BEAT SATAN | The Binding Of Isaac Afterbirth Gameplay [Ninten…
172.3K viewsAug 21, 2017
YouTubeYuB
20:53
binding of isaac? more like ASDHKJFAKJSDFJLASKDJF
97.4K viewsJan 24, 2023
YouTubeYuB
34:14
isaac: the ultimate choke
408.3K viewsAug 1, 2019
YouTubeYuB
See more videos
Static thumbnail place holder

Short videos

0:23
Can YOU Guess All THESE Imitated ITEMS in The Bind…
17.4K views22 hours ago
YouTube🜏El Mapache of Isaac🜏
0:09
[OUT] Beating a Room a Day, DAY 251 #gaming #binding…
1.1K views2 days ago
YouTubeAnother Matt Playing Isaac
0:23
Can YOU Guess All THESE Hidden Imitated ITEMS in T…
950 views4 days ago
YouTube🜏El Mapache of Isaac🜏
1:25
El Mejor Desafio del Binding of Isaac #thebindingofisaac
918 views1 day ago
YouTubeMilo-chiro
1:01
More Challenges That Help You Win More in The Bindi…
332.3K views3 months ago
YouTubeAdrian
1:27
These Challenges Help You Win More in The Binding o…
249K views3 months ago
YouTubeAdrian
0:29
The Best Challenges for Beginner Players🔥 Part 1
31.4K views2 months ago
YouTubeInCubei
1:12
The Solution Was Quite Interesting And Exotic, Giv…
814.6K viewsDec 22, 2024
YouTubeKayhos
0:23
Can YOU Guess THESE Imitated ITEMS !? The Bind…
68.1K views2 months ago
YouTube🜏El Mapache of Isaac🜏
1:00
Completing the Isaac's Awakening challenge in Th…
30.5K views10 months ago
YouTubeMastaaNasty
0:17
This Is Why I Can't Win A Single Run.. #thebindingofi…
17.1K views2 days ago
YouTubeKayhos
0:57
Tainted Lost SKILL ISSUE
1K views2 days ago
YouTubeBrofessorSky
1:08
Only Keys Challenge in Isaac is BRUTAL
7.7K views4 months ago
YouTubeBrofessorSky
0:17
This Is Why I Can't Win A Single Run.. #thebindingofi…
2 views2 days ago
YouTubeKayhos
1:02
Average Streamer Luck In Isaac
662 views16 hours ago
YouTubeBrofessorSky
0:14
EVERYBODY GET IN THE CAR NOW - IB @Riiverking …
584 views3 days ago
YouTubeipecacdotzip
0:46
Unleashing Berserk Mode! in The Binding of Isaac #shorts
165 views3 days ago
YouTubedonnell187
0:45
Enter the Gungeon Moments that Will Make Your Heart S…
150 views1 day ago
YouTubeWiibz
0:49
BEST Unlocks for Lilith and Tainted Lilith
28.8K viewsDec 16, 2024
YouTubeCyanLyon
0:49
BEST Unlocks for Eve and Tainted Eve
8.8K viewsDec 13, 2024
YouTubeCyanLyon
Static thumbnail place holder