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Pathophys: Autosomal dominant, genetic mutations affecting cardiac sarcomere proteins; Variable phenotypic penetrance Signs / symptoms: +/- asymptomatic Exertional dyspnea, fatigue, angina, lightheadedness, syncope Systolic ejection murmur, worse with ↓ LV blood vol. Diastolic dysfunction with audible S4 ↑ Risk for afib & vtach Diagnosis ...
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