US Daily Media on Instagram: ""The Big C" is an American television dramedy that aired on Showtime from 2010 to 2013. It stars Laura Linney as Cathy Jamison, a suburban wife and high school teacher who is diagnosed with terminal melanoma (a form of cancer). Instead of revealing her illness to her family right away, she decides to make dramatic changes in her life and truly start living — with boldness, honesty, and sometimes recklessness. Overview: Genre: Comedy-drama Creator: Darlene Hunt Seaso