Identification Summary Promethazine is a first-generation antihistamine used for the treatment of allergic conditions, nausea and vomiting, and motion sickness.

Promethazine, sold under the brand name Phenergan among others, is a first-generation antihistamine, sedative, and antiemetic used to treat allergies, and nausea.

Objective: This review of promethazine explores its pharmacology and history of toxicities, and discusses current recommendations from patient safety organizations, which implicate its role in …

Promethazine is defined as a derivative of phenothiazine that exhibits strong antihistamine activity and has effects on the central nervous system. It is used to treat allergic conditions and enhance the …

Feb 17, 2020 · Includes Promethazine indications, dosage/administration, pharmacology, mechanism/onset/duration of action, half-life, dosage forms, interactions, warnings, adverse …

Promethazine Administration Type: Antiemetic; Phenothiazine Derivative; Sedative Dosage Forms: 12.5mg, 25mg, 50mg; 6.25mg/5 mL sol; IM; IV Routes of Administration: Oral Common Trade …

Jul 17, 2024 · It acts on muscarinic acetylcholine receptors, which are part of the parasympathetic nervous system. By blocking these receptors, promethazine can reduce the activity of the …

Feb 29, 2024 · For motion sickness, promethazine is usually started within 1 hour before traveling. When used for surgery, promethazine is usually taken the night before the surgery.

Promethazine also blocks the acetylcholine on the muscarinic receptors, thus suppressing the nausea and vomiting and contributing to the calming down of symptoms of motion sickness.

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