Tolebrutinib failed to meet the primary endpoint in the phase 3 PERSEUS study involving patients with primary progressive multiple sclerosis.

The American Headache Society updates guidelines on the use of parenteral pharmacologic therapies for migraine attack management in the ED.

Cognitive impairment is positively associated with neuropsychiatric symptoms in both individuals with Down syndrome and older adults without Down syndrome.

Flow is a transcranial direct current stimulation device that delivers low-intensity direct electrical current to specific areas of the brain.

Ginkgo biloba and several other therapies offer modest cognitive benefits in vascular cognitive impairment, but heterogeneous evidence limits certainty.

In pediatric-onset multiple sclerosis, switching to oral or infusion therapies was linked to fewer relapses than switching between injectable treatments.

Surgical supply lists optimized using historical data may reduce hospital costs and waste while increasing operational efficiency.

The Radiological Society of North America held a conference covering a wide range of new trends and information in radiological research.

Pediatric care is more difficult to access as the number of low-capability pediatric hospitals has more than doubled between 2003 and 2022.

Prehabilitation can reduce disability after surgery in older adults with frailty when compared with usual care.

Adolescents and young adults with stage IV cancer have unique primary tumor sources and survive longer with synchronous brain metastases than older adults.

Exposure to excessive heat is shown to negatively impact early childhood development, with a pronounced impact on disadvantaged groups.