A 34-year-old man was admitted to the hospital because of left ear pain with hearing loss and facial droop on the left side.

Preclinical and observational studies suggest that exercise may improve cancer outcomes. However, definitive level 1 evidence ...

A new report from the National Academy of Medicine proposes a research agenda to address climate-related health risks and data gaps, emphasizing equity, innovation, and interdisciplinary collaboration ...

In the peripheral airways of patients with chronic obstructive pulmonary disease, as compared with normal peripheral airways, there is airflow limitation due to a variable mixture of loss of ...

Next-generation sequencing has enabled precision therapeutic approaches that have improved the lives of children with rare diseases. Congenital diarrhea and enteropathies (CODEs) are associated ...

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when ...

Chronic spontaneous urticaria is an idiopathic syndrome defined by recurring itch, hives, or angioedema (or a combination of these symptoms) for more than 6 weeks. Remibrutinib, an oral, highly ...

The case description for a Case Records of the Massachusetts General Hospital appears below. A 72-year-old woman with type 2 diabetes had somnolence after a urologic procedure for bladder cancer.

Familial HLH is a success story in modern medicine. Initially a disease that was largely unknown and fatal, it is now understood on a molecular level and is curable. Moreover, HLH is an archetype ...

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when ...

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when ...

Primary central nervous system (CNS) vasculitis is a rare, frequently misdiagnosed condition that affects the brain and spinal cord and is characterized by a variety of neurologic symptoms at ...