Background To compare relapse and disability outcomes of inebilizumab, azathioprine (AZA), mycophenolate mofetil (MMF) and rituximab (RTX) in maintenance-therapy-naive patients with aquaporin-4 ...

Background Childhood-onset epilepsy has been linked to poor school performance but limited evidence exists for long-term educational achievement. We examined educational achievement from adolescence ...

Background Ofatumumab and ocrelizumab are widely used high-efficacy anti-CD20 therapies for relapsing-remitting multiple sclerosis (RRMS), but direct comparative evidence remains limited. We aimed to ...

Background To investigate whether exposure to pet hamsters may act as a potential trigger for autoimmune cerebellar ataxia (ACA). Methods We conducted a hospital-based case–control study based on our ...

Focused ultrasound (FUS) is an emerging technology that uses ultrasound waves to ablate or modulate tissue. While it has been explored in several different clinical fields for over two decades, it has ...

Mummery et al 1 outline the recommendations for the appropriate use (AURs) of the amyloid-targeting monoclonal antibody lecanemab in clinical practice in the United Kingdom. These recommendations are ...

Background Plasma phosphorylated tau (p-tau) 217 test has emerged as a minimally invasive and accessible alternative to positron emission tomography imaging and cerebrospinal fluid analysis for ...

Background We report our experience of patients with generalised myasthenia gravis (gMG) treated with efgartigimod, an neonatal Fc receptor antagonist, under the Early Access to Medicine Scheme (EAMS) ...

Myasthenia gravis (MG) treatment’s landscape has dramatically changed with the approval of novel therapeutics that can provide rapid improvement, including in patients typically considered refractory.

Background Type II spinal muscular atrophy (SMA) often leads to scoliosis in up to 90% of cases. While pharmacological treatments have shown improvements in motor function, their impact on scoliosis ...

Correspondence to Professor Bart C Jacobs, Neurology and Immunology, Ee2289, Erasmus Medical Center, Rotterdam, 3015 GD, The Netherlands; b.jacobs{at}erasmusmc.nl Background This study aimed to ...

Correspondence to Dr Brigid Ryan, Department of Anatomy and Medical Imaging, The University of Auckland, Auckland 1142, New Zealand; b.ryan{at}auckland.ac.nz Introduction Young-onset dementia ...