Live updates from American Family Field as Milwaukee's Jacob Misiorowski faces off against Pittsburgh's Paul Skenes.

Pittsburgh Pirates star Paul Skenes faced off against Milwaukee Brewers rookie sensation Misiorowski. And Skenes, who has arguably had the nastiest stuff of any big-league starter since the day he debuted, lost to a pitcher whose stuff simply looked nastier than his.

If Milwaukee Brewers pitcher Jacob Misiorowski was intimidated by the prospect of going head-to-head with Pittsburgh Pirates ace Paul Skenes, the rookie didn't show it. Misiorowski out-dueled the Pirates' star Wednesday in just his third major-league start during a 4-2 Brewers victory.