The endothelial glycocalyx integrates mechanical signals with vascular biology, playing a vital role in health and disease, ...

How the gut microbiome, systemic inflammation, and metabolic health link cardiovascular disease and prostate disorders—and ...

Receptor activator of nuclear factor kappa B ligand (RANKL) is a multifunctional cytokine and has been attracting high levels of interest in broader fields of biomedical sciences. In this study, we ...

An international research team led by MDI Biological Laboratory President Hermann Haller, M.D. and postdoctoral researcher Yannic Becker, Ph.D. has discovered that a little-known molecule, heparanase ...

Yannic Becker https://orcid.org/0009-0009-1050-9509 [email protected] Department of Nephrology, Institute of Functional and Applied Anatomy, Hannover Medical School ...

The vascular endothelium is the largest organ in the human body, capable of performing a wide range of cellular signaling and synthetic functions. It is also subjected to considerable mechanical ...

Angiopoietin-like 4 (ANGPTL4) is a multifunctional glycoprotein that regulates several crucial biological processes, including glucose and lipid metabolism, vascular permeability, wound healing, ...

Abstract Angiotensin II (Ang II) has been implicated in the pathogenesis of the vascular injury associated with hypertension and diabetes mellitus. Increased vascular permeability is an important ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Capillary leakage is a hallmark of severe dengue, yet its precise mechanisms remain ...

ABSTRACT: Gastric cancer (GC) is one of the most common cancers in the world and the leading cause of cancer-related death in China. At present, the intervention measures for GC are limited. Therefore ...

ABSTRACT: Background: Exudative, or “wet” age-related macular degeneration (wAMD), characterized by choroidal neovascularization and consequent accumulation of subretinal fluid, is the leading cause ...