In a new study, published in Cell, researchers describe a newfound mechanism for creating proteins in a giant DNA virus, comparable to a mechanism in eukaryotic cells. The finding challenges the dogma ...

Brandt Eichman and Walter Chazin, professors of biochemistry, have worked together to provide a better understanding of how exactly DNA replication is initiated in eukaryotes. Using Vanderbilt's state ...

Regulated helicase activation by DDK kinase is central for genome stability. However, how DDK phosphorylation primes the MCM2-7 double hexamer (DH) for Sld3-Sld7 binding and Cdc45 loading remained ...

A collaborative research team led by Hiroyuki Imachi and Masaru K. Nobu of the Japan Agency for Marine-Earth Science and ...

Prokaryotic single-celled organisms, the ancestors of modern-day bacteria and archaea, are the most ancient form of life on our planet, first appearing roughly 3.5 billion years ago. The first ...

For foreign DNA to make it into a eukaryotic cell’s genome, DNA must first enter the cell, then cross the nuclear envelope, and finally insert itself into the genome. Below are a number of proposed ...

Another potentially game-changing discovery has come out of the lab of Feng Zhang, PhD. This time, they uncovered the first programmable RNA-guided system in eukaryotes. Just a few months ago, the ...

The origin of complex cells started without oxygen, new research suggests. Since the 1960s, many experts have argued that the emergence of eukaryotes (cells containing a clearly defined nucleus) ...