Experimental laboratory and mouse studies found that PGK1’s non-canonical kinase activity promotes degradation of a host ...
A peer-reviewed review proposes that chronic DNA damage response signaling may connect senescence, inflammation and other ...
ATF3-dependent IL-9 production by GITR-stimulated ILC2s promotes eosinophil accumulation and cytotoxic tumor control.
Learn how researchers at St. Jude, led by Hai Dao, PhD, discovered the mechanisms behind PARP1-mediated DNA repair.
The ATR–ATRIP kinase complex safeguards genome integrity by coordinating cellular responses to DNA damage and replication stress. Two recent cryo-EM studies resolve the structural basis of ATR–ATRIP ...
Plant DNA viruses — including double-stranded DNA viruses such as caulimoviruses and single-stranded DNA viruses such as ...
Viruses are sneaky intruders, hijacking the internal machinery of host cells and replicating out of sight. Understanding these dynamics is the first step to developing effective antiviral strategies ...
Wee1 inhibitors are a promising new cancer treatment, but serious side effects threaten their adoption in the clinic. Now, ...
Publication of first ever head-to-head comparison of gut microbiome changes associated with novel oral preclinical PolC (pol IIIC*) inhibitors to linezolid in a murine neutropenic thigh infection ...
Kiszala, the CEO and co-founder of intoDNA, to explore how a breakthrough in understanding DNA damage and repair could ...
Increasing the RNA-processing factor SRSF1 shifted aged human skin cells toward younger molecular profiles while preserving ...
Bacteriophages, or viruses that infect bacteria, have a fiendishly simple purpose in life: attach to a bacterial cell, inject ...
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