Learn how researchers at St. Jude, led by Hai Dao, PhD, discovered the mechanisms behind PARP1-mediated DNA repair.

Plant DNA viruses — including double-stranded DNA viruses such as caulimoviruses and single-stranded DNA viruses such as ...

Viruses are sneaky intruders, hijacking the internal machinery of host cells and replicating out of sight. Understanding these dynamics is the first step to developing effective antiviral strategies ...

Wee1 inhibitors are a promising new cancer treatment, but serious side effects threaten their adoption in the clinic. Now, ...

Publication of first ever head-to-head comparison of gut microbiome changes associated with novel oral preclinical PolC (pol IIIC*) inhibitors to linezolid in a murine neutropenic thigh infection ...

Called Cas12a2, the CRISPR system had some distinctive properties. Rather than editing cells’ DNA when prompted by a guide RNA, as CRISPR-Cas9 does, Cas12a2 indiscriminately shreds it, ultimately ...

Kiszala, the CEO and co-founder of intoDNA, to explore how a breakthrough in understanding DNA damage and repair could ...

New research shows that the NarL protein binds directly to the promoter of the DNA repair gene ogt in Salmonella Typhimurium, ...

Increasing the RNA-processing factor SRSF1 shifted aged human skin cells toward younger molecular profiles while preserving ...

Human genomic DNA is wrapped around core histone proteins to form nucleosomes, the fundamental units of chromatin. During interphase, the period ...

Human genomic DNA is wrapped around core histone proteins to form nucleosomes, the fundamental units of chromatin.

A new review in the Journal of Translational Medicine consolidates how the replication-initiation protein ORC1 safeguards ...