Every cell in the human body faces a chronic challenge: protecting its DNA. Whenever cells divide, their genetic material must be copied accurately. But DNA is continuously under attack, and when ...

A mouse embryo has now been made to write its own family tree. A recording device called the DNA Typewriter, built in Jay Shendure’s laboratory at the University of Washington, kept a running log of ...

Reading 2,357 single neurons, a Nature study found widespread DNA damage in a quarter of fetal brain cells and a purge around ...

A damaged patch of adult brain tissue can trigger nearby support cells to stretch, divide, and send newly formed nuclei into the empty space, revealing a repair response more flexible than scientists ...

Researchers report that the RNA-processing protein ALYREF binds poly-ADP-ribose at DNA double-strand breaks, delaying repair ...

Single-cell profiling of nearly 2,000 people brings scientists closer to understanding the link between genetic variation, gene expression and health.

Researchers built an in-cell ELISA that measures the DNA damage marker γH2AX in stable, non-proliferating human hepatocytes ...

Scientists reconstructed a family tree of 1.28 million cells in a mouse embryo, revealing how cells develop into different ...

A previously unknown mechanism required for cells to start proliferating has been identified. A combination of mathematical modelling and cell-based experiments shows that the enzyme WEE1 switches off ...

Scientists have discovered how pancreatic cancer cells continually reshape their genetic makeup to become more aggressive, ...

Study demonstrates enhanced immune cell activation in poultry, using scientific discovery that had been shelved for decades.

A molecular tracking technology called DNA Typewriter can record the cellular lineage of a mouse embryo, from a single cell to over a million.