Single-cell profiling of nearly 2,000 people brings scientists closer to understanding the link between genetic variation, gene expression and health.

Researchers report that the RNA-processing protein ALYREF binds poly-ADP-ribose at DNA double-strand breaks, delaying repair ...

Scientists reconstructed a family tree of 1.28 million cells in a mouse embryo, revealing how cells develop into different ...

Researchers built an in-cell ELISA that measures the DNA damage marker γH2AX in stable, non-proliferating human hepatocytes ...

A family of mutations seen in about 20% of human cancers drives malignancy by changing the accessibility of genes to a ...

"I've never smoked a cigarette in my life, so I won't get lung cancer." "There are no smokers in my family, so I'm safe."If ...

A previously unknown mechanism required for cells to start proliferating has been identified. A combination of mathematical modelling and cell-based experiments shows that the enzyme WEE1 switches off ...

Eight Myotis genomes connect unusual immune adaptations with DNA repair, cell death and dramatic differences in lifespan.

In Greek mythology, Narcissus, renowned for his handsome appearance, rejected the love of Echo, a nymph who repeated others’ ...

Researchers at the University of Chicago identified a mechanism to make immune cells reprogrammed by radiation therapy attack ...

A Weissman Lab team combined heritable DNA barcodes with gene expression and spatial data to reconstruct the family trees of ...

The deadliest form of skin cancer, melanoma, kills more than 8,000 Americans a year and in Connecticut, nearly 900 people ...