LJI Professor Stephen Schoenberger, Ph.D. LA JOLLA, CA—Scientists at La Jolla Institute for Immunology (LJI) and the University of Washington (UW) have discovered that patients with lupus have unusual ...
A collaboration with various centers of the Human Immune Profiling Consortium (HIPC) to build upon the existing infrastructure of ImmPort, a publicly-available data repository, which includes ...
As our knowledge of the FceRI-mediated signal transduction has grown for the last two decades, the need to study in vivo roles of this pathway in disease settings encouraged the Kawakami group to ...
Dr. Kawakami has been using the high-affinity IgE receptor (FceRI) signaling in mast cells as a model system. Following his co-discovery of two Tec family PTKs, Btk and Itk, in mast cells, his group ...
The lab investigates T cell reactivity and disease progression in Parkinson’s disease. Findings suggest immune cells are responsible for disease onset. Early interference with T cell responses could ...
It is thought that an interaction between predisposing genes and environmental factors, such as viral infections, may trigger T1D. Several viruses, mainly from the Enterovirus genus have been ...
Since their finding of ‘monomeric IgE effects’ on mast cell survival in 2001, Dr. Kawakami and associates have shown that IgEs exhibit a tremendous heterogeneity in their ability to induce mast cell ...
As part of the President’s Award Celebration, LJI leaders announced a $55 million fundraising campaign to launch a new ...
In 2013, Dr. Vijayanand teamed up with Professor Christian Ottensmeier at the Cancer Center, University of Southampton, UK, to set up a large patient-centered cancer immunology program utilizing ...
Research suggests that GLP-1 medications may have anti-inflammatory effects and influence the activity of certain immune cells, including T cells.
During the course of the above-mentioned study, they found interactions between Btk and protein kinase C (PKC)-b and terreic acid as a novel Btk inhibitor that blocked Btk-PKC-b interactions. Their ...
The La Jolla Institute for Immunology is dedicated to understanding the intricacies and power of the immune system so that we may apply that knowledge to promote human health and prevent a wide range ...
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