EMBO Press1d
Getting to the heart of cardiovascular complications associated with inflammatory arthritis
Inflammatory arthritis encompasses a group of autoimmune diseases, including rheumatoid arthritis (RA), psoriatic arthritis ...
EMBO Press2d
Metabolic reaction fluxes as amplifiers and buffers of risk alleles for coronary artery disease
Using genetically predicted metabolic reaction fluxes, the authors identify reactions that can amplify or buffer the effect ...
The EMBO Journal3d
T-cell-derived IFN-γ suppresses T follicular helper cell differentiation and antibody responses
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Subcutaneous LCMV infection induces T H 1 cell ...
The EMBO Journal4d
Multi-epitope immunocapture of huntingtin reveals striatum-selective molecular signatures
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Huntington’s disease (HD) is a debilitating ...
The EMBO Journal4d
T-cell-derived IFN-γ suppresses T follicular helper cell differentiation and antibody responses
This cover highlights the article PLK1 inhibition delays mitotic entry revealing changes to the phosphoproteome of mammalian cells early in division by M. Gobran, P. Lenart and colleagues. HeLa Kyoto ...
The EMBO Journal4d
Proteomics and personalized PDX models identify treatment for a progressive malignancy within an actionable timeframe
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Genomics has transformed the diagnostic ...
The EMBO Journal4d
Dimerization of GAS2 mediates crosslinking of microtubules and F-actin
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The spectraplakin family protein GAS2 was ...
The EMBO Journal4d
Saccharin disrupts bacterial cell envelope stability and interferes with DNA replication dynamics
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Saccharin has been part of the human diet for ...
The EMBO Journal4d
The biochemical mechanism of Rho GTPase membrane binding, activation and retention in activity patterning
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Rho GTPases form plasma membrane-associated ...
EMBO Press4d
Mouse promoters are characterised by low occupancy and high turnover of RNA polymerase II
Single-Molecule Footprinting reveals that RNA polymerase II (Pol II) occupancy is infrequent at mouse promoters. This results ...
The EMBO Journal5d
SIRT5-mediated desuccinylation of PPA2 enhances HIF-1alpha-dependent adaptation to hypoxic stress and colorectal cancer metastasis
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Metastasis is the primary cause of death in ...
The EMBO Journal5d
HAND1 level controls the specification of multipotent cardiac and extraembryonic progenitors from human pluripotent stem cells
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Diverse sets of progenitors contribute to the ...