Objectives To report population-level data describing long-term trends in remission, sustained remission and relapse among ...

is an open access, peer reviewed rheumatology journal that publishes original research on musculoskeletal disorders and rheumatic conditions ...

Objectives The oral microbiome plays a critical role in modulating systemic inflammation, partly through its interactions with the gut microbiome. Although gut microbiome dysbiosis has been implicated ...

Background Cardiovascular disease and osteoarthritis (OA) share risk factors, but the link between comprehensive cardiovascular health and OA incidence is unclear. We investigated the association of ...

Objective To assess prevalence, associated disability and pain burden of the main rheumatic and musculoskeletal diseases (RMDs): rheumatoid and non-rheumatoid inflammatory arthritis, knee, hip and ...

What is already known on this topic Low-dose glucocorticoids (≤7.5 mg/day prednisone equivalent) are frequently used as a long-term cotreatment for rheumatoid arthritis in real-world settings. Trials ...

Objective To present updated integrated safety analyses of bimekizumab in patients with axial spondyloarthritis (axSpA) or psoriatic arthritis (PsA). Methods Safety data pooled from six phase IIb/III ...

Objective Cardiac involvement is a major complication of systemic sclerosis (SSc), with myocardial fibrosis as a hallmark feature. Cardiovascular magnetic resonance (CMR) is used to detect cardiac ...

Objectives This study aimed to develop and validate a prediction model for the future progression of difficult-to-treat rheumatoid arthritis (D2T RA) and support the precise use of biologic and ...

Objective Interstitial lung disease (ILD) represents the most common and severe organ manifestation observed in patients diagnosed with connective tissue diseases (CTDs). The aim of this retrospective ...

Objectives This 1-year long-term extension (LTE) study (NCT04451772) followed the 48-week phase 2 SLEek study (NCT03978520) that evaluated upadacitinib (a Janus kinase inhibitor) alone or combined ...

Background Unravelling the performance of disease activity measures in peripheral spondyloarthritis (pSpA) is crucial for the development of clinical studies. We aimed to evaluate the construct ...