The Seattle Mariners (25-19) and the San Diego Padres (27-17) wrap up a 3-game interleague series Sunday at Petco Park in San Diego. First pitch is scheduled for 4:10 p.m. ET. Let's analyze BetMGM Sportsbook's MLB odds around the Mariners vs. Padres odds and make our expert MLB picks and predictions for the best bets.

T he Seattle Mariners began their 10-game road trip as well as it could have. The Mariners beat the San Diego Padres 6-1 Sunday at Petco Park. Seattle secured a sweep over the San

Get San Diego vs Seattle baseball betting preview, spread and over/under insights for their matchup on May 18.

The Seattle Mariners starting rotation is finally starting to work its way back to full strength after being bit by the injury bug this season. And the performa

MLB player prop bets and odds for Miguel Antonio Vargas on Wednesday, May 21, 2025, as the Chicago White Sox take on the Seattle Mariners.

Evans used a steady diet of fastballs to keep the vaunted San Diego Padres ' lineup of heavy hitters off-stride. It worked as the Mariners posted a 5-1 win over the Padres at Petco Park. The young Mariners' prospect was able to not only pitch well, but he's been listening closely to the MLB pitching staff.

The Padres are favored at home (-170) against the Mariners (+143). The matchup on the mound for this contest is set with the San Diego Padres looking to Nick Pivetta (5-2), and Emerson Hancock (1-2) taking the ball for the Seattle Mariners.

Cease kept the score 1-0 until a questionable ball four call against Alejandro Kirk allowed him to start the bottom of the fifth inning with a leadoff walk. A struggling Anthony Santander was able to get to an inside pitch and hit a line drive home run to right field to put Toronto up, 3-0.