HotSpot Therapeutics, Inc., a biotechnology company pioneering the discovery and development of oral, allosteric small molecules that target natural regulatory pockets, today announced it will present ...
Single-cell profiling of nearly 2,000 people brings scientists closer to understanding the link between genetic variation, gene expression and health.
The rapid increase in the availability of genomic data has transformed plant breeding by enabling the prediction of complex ...
A GWAS and genomic prediction study in tetraploid pot carnation identified genomic regions linked to seven of eight ...
A combined GWAS and TWAS study of large multi-location soybean panels identified six QTLs and six putative candidate genes ...
You will be redirected to our submission process. The family Brassicaceae comprises approximately 350 genera and 3,000 species, encompassing many economically important crops, including edible and ...
Mutualistic interactions are hypothesized to broaden ecological niches and promote diversification, yet evidence for this relationship remains limited. This study finds that, across Poa grasses, ...
Chronic Obstructive Pulmonary Disease (COPD) is a complex, progressive, and multifaceted disease, and because there are no ...
A research team has shown that daily hyperspectral measurements can expose how genetic differences shape photosynthesis, ...
非性状相关组织产生误导性TWAS信号。研究人员以GCK和血糖为例说明：胰腺本应是相关组织，但GCK在胰腺缺乏eQTL信号；相反，胫神经和甲状腺等无关组织中出现强且共定位的TWAS信号，方向却与生物学预期相反。模拟显示，当非相关组织表达与因果组织表达呈反向协同时，FSR最高；高LD可使非因果组织eQTL借助同一单倍型通过共定位过滤。限定单组织特异性蛋白后，FSR由23%降至20%，排除脑特异性蛋白后 ...
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