Researchers built an in-cell ELISA that measures the DNA damage marker γH2AX in stable, non-proliferating human hepatocytes ...

Mutations found in about 20% of human cancers may promote malignant growth through a shared change in how DNA is organized, ...

A Weissman Lab team combined heritable DNA barcodes with gene expression and spatial data to reconstruct the family trees of ...

High-grade serous ovarian cancer is an aggressive form of ovarian cancer, characterized in particular by high diversity among ...

Cancer cells that have lost one safeguard against DNA damage can become dependent on another, an enzyme called Wee1. Drugs ...

Single-cell profiling of nearly 2,000 people brings scientists closer to understanding the link between genetic variation, gene expression and health.

A previously unknown mechanism required for cells to start proliferating has been identified. A combination of mathematical modelling and cell-based experiments shows that the enzyme WEE1 switches off ...

A study in chicken cells found that the CCAN kinetochore complex forms a spherical shell whose assembly and ...

Near-complete genomes from eight Myotis bat species suggest that viral defense, DNA-damage responses, cancer-related pathways and extreme longevity have evolved through overlapping biological ...

Scientists reconstructed a family tree of 1.28 million cells in a mouse embryo, revealing how cells develop into different ...

Scientists have discovered how pancreatic cancer cells continually reshape their genetic makeup to become more aggressive, ...

Study demonstrates enhanced immune cell activation in poultry, using scientific discovery that had been shelved for decades.