Ultra-deep long-read sequencing has delivered the first telomere-to-telomere sequence of the non-Mendelian ribosomal DNA ...

Almost every cell in our body contains around two meters (6.6 feet) of DNA, packed into a tiny nucleus. Yet for the cell to ...

Among the many marvels of life is the cell's ability to divide and thus enable organisms to grow and renew themselves. For this, the cell must duplicate its DNA—its genome—and segregate it equally ...

In the 1930s, Hermann Muller was the first researcher to note that the ends of chromosomes had unique properties. Muller ...

A new BMC Biology study shows that chromosomal inversions in Anopheles mosquitoes reshape 3D genome folding and rewire ...

Scientists have discovered a new property of the molecular motors that shape our chromosomes. While six years ago they found that these so-called SMC motor proteins make long loops in our DNA, they ...

Small, cancer-associated DNA circles "hitchhike" on chromosomes during cell division to spread efficiently to daughter cells by co-opting a process used to maintain cellular identity through ...

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published in Nature. Subscribe to our newsletter for the latest sci-tech news updates.

Noah A. Dusseau is in the Department of Physiology, College of Natural Science, Michigan State University, East Lansing, Michigan 48824, USA. Read the paper: Genetic elements promote retention of ...

The body cells of humans and animals contain a double set of chromosomes. One half of the genetic material comes from the mother, the other stems from the father. During the formation of sperm or egg ...

Researchers have uncovered the enzyme behind chromothripsis, a chaotic chromosome-shattering event seen in about one in four cancers. The enzyme, N4BP2, breaks apart DNA trapped in tiny cellular ...

Chromosomes are masters of organization. These long strings of DNA fold down into an ensemble of compact structures that keep needed parts of the genome accessible while tucking away those that aren’t ...