The San Francisco 49ers could be without another key offensive player this week after All-Pro tight end George Kittle missed practice with a sore hamstring. The Niners are lost All-Pro running back Christian McCaffrey and star receiver Deebo Samuel to injuries before Kittle reported soreness in his hamstring after Wednesday's practice.

George Kittle and Charvarius Ward sat out Thursday's practice with injuries for the 49ers, who are already dealing with injuries to Christian McCaffrey and Deebo Samuel.

George Kittle missed practice on Thursday because of a hamstring injury. Here's the latest on the TE's status for the Week 3 49ers vs. Rams game.

San Francisco 49ers quarterback Brock Purdy is still making quite an impact in the state of Iowa despite being three years removed from his playing days for the Cyclones. Purdy and the Niners will play in one of three games that will air on Fox during the later slate of games at 1 p.

The 49ers QB became a better vocal leader this offseason. How will that help him overcome injuries to Deebo Samuel Sr. and Christian McCaffrey?

San Francisco 49ers quarterback Brock Purdy isn't letting early-season injuries shake his confidence. Although he has been without reigning NFL Offensive Player of the Year Christian McCaffrey for the first two games—McCaffrey will miss at least the next three with Achilles tendinitis—Purdy remains optimistic.