CAPE GIRARDEAU, Mo. (WSIL) -- A fire claimed the lives of two people in Cape Girardeau on Wednesday afternoon.

Parking restrictions will be in place in Cape Girardeau due to the Old Town Cape Parade of Lights on Sunday, November 30, ...

NEW MADRID, Mo. (WSIL) -- One person was seriously injured after a crash along I-55 in New Madrid County on Tuesday evening.

Today, prepare for gusty winds that will make it feel cold, even with sunshine. For areas north of Interstate 64, we've seen ...

Cape Girardeau Public Schools announced the promotion of Dr. Brock Crowley to Assistant Superintendent of Support Services.

Rose Dexter was just a month old in August when she developed constipation, gas and tummy discomfort, symptoms that her ...

Deputies from the Williamson County Sheriff's Office responded to a report of a stabbing on November 24 after 11 p.m.

Hunters in Illinois harvested a preliminary total of 51,409 deer during the first weekend of the Illinois firearm deer season ...

It’s time to brace ourselves for a significant shift in our weather pattern here in Southern Illinois and surrounding areas.

A boil water order has been issued for several areas due to a water line break, according to De Soto Superintendent of Public ...

The City of Cape Girardeau Regional Airport is set to host a ribbon-cutting ceremony for its new flight service to ...

The City of Carbondale is advising residents about illegal materials that should not be flushed or poured down drains. These ...