As part of the President’s Award Celebration, LJI leaders announced a $55 million fundraising campaign to launch a new ...
In 2013, Dr. Vijayanand teamed up with Professor Christian Ottensmeier at the Cancer Center, University of Southampton, UK, to set up a large patient-centered cancer immunology program utilizing ...
A T cell (pictured) can have many roles in the immune system. (Image courtesy NIAID) LA JOLLA, CA—According to new research in the journal Immunity, T cells have a nuclear receptor doing something ...
LA JOLLA—The La Jolla Institute for Immunology (LJI) is partnering with Synbal, Inc., a preclinical biotechnology company based in San Diego, CA, to develop multi-gene, humanized mouse models for ...
Research suggests that GLP-1 medications may have anti-inflammatory effects and influence the activity of certain immune cells, including T cells.
During the course of the above-mentioned study, they found interactions between Btk and protein kinase C (PKC)-b and terreic acid as a novel Btk inhibitor that blocked Btk-PKC-b interactions. Their ...
Dr. Kawakami has been using the high-affinity IgE receptor (FceRI) signaling in mast cells as a model system. Following his co-discovery of two Tec family PTKs, Btk and Itk, in mast cells, his group ...
As our knowledge of the FceRI-mediated signal transduction has grown for the last two decades, the need to study in vivo roles of this pathway in disease settings encouraged the Kawakami group to ...
The histopathologic features of human type 1 diabetes are remarkably heterogeneous throughout the pancreas. One lobule of the organ can appear completely unaffected by the ongoing autoimmune disease, ...
The lab investigates T cell reactivity and disease progression in Parkinson’s disease. Findings suggest immune cells are responsible for disease onset. Early interference with T cell responses could ...
LA JOLLA, CA—Scientists at La Jolla Institute for Immunology (LJI) have uncovered the structure and function of the first FDA-approved treatment for Zaire ebolavirus (Ebola virus). Inmazeb (REGN-EB3), ...
LA JOLLA, CA and PRINCETON, NJ – A 35-year academic-industry partnership that has produced groundbreaking discoveries in immunology and supported first-in-class therapies for rare disease patients has ...
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