The bald figures show U.K. biotech continues to attract funding, but two new reports highlight the ongoing structural weakness of dependence on overseas investors and a lack of the domestic capital ...
Xencor Inc. plans to talk with the U.S. FDA next year about the possibility of accelerated approval for XmAb-819, an ENPP3xCD3 T-cell engaging bispecific antibody, in patients with advanced clear cell ...
The 2026 European Society of Medical Oncology (ESMO) 2026 annual meeting kicked off with a bit of drama, as Merck & Co. Inc.
Cambridge, Mass.-based Alkeus Pharmaceuticals Inc.’s dosing this summer of the first patient in its phase III Northstar study ...
Researchers from Recludix Pharma Inc. presented preclinical data on first-in-class inhibitors of the Bruton tyrosine kinase (BTK) SH2 domain, a novel approach for the treatment of multiple sclerosis ...
Ascletis Pharma Inc. has submitted an IND application to the FDA for ASC-39 oral tablets, an oral small-molecule selective amylin receptor agonist, for the treatment of obesity. A phase I trial is ...
Researchers from Oregon Health & Science University investigated the potential of SU-056, a small-molecule Y-box binding protein 1 (YB-1) inhibitor, to directly suppress osteosarcoma and improve ...
Evotec International GmbH has prepared and tested new compounds acting as NLRP3 inflammasome inhibitors reported to be useful for the treatment of inflammatory and neurological disorders, asthma, ...
Effector memory T cells (TEMs) play a crucial role in the pathogenesis of autoimmune diseases such as inflammatory bowel disease (IBD), and they highly express the voltage-gated potassium channel Kv1.
Idiopathic membranous nephropathy (IMN) is frequently driven by autoantibodies targeting phospholipase A2 receptor 1 (PLA2R), resulting in immune-mediated glomerular injury and proteinuria.
CSIC (Consejo Superior de Investigaciones Científicas) and the Universidad Autónoma de Madrid have patented new HSV-1 pUL15C nuclease inhibitors potentially useful for the treatment of herpes simplex ...
A consortium funded by the National Institutes of Health has unveiled the most comprehensive map of somatic mosaicism to date ...
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