A new study has pointed out that Molnupiravir treatment increases the ratio of transition to transversion mutations in COVID-19 patients and that the treatment does not appear to induce resistance ...

Max Planck scientists find a novel way to construct transition states for protein folding reactions.

Points are positioned according the proportion of the branch’s mutations that are G-to-A (x) or any transition mutation (y), and coloured by the year in which they occurred.

A new study suggests that the antiviral Molnupiravir may “paradoxically” be driving COVID-19 mutations, creating variants of concern. What is going on? It is all about molnupiravir’s mode of action ...

The agreement gives Beam the exclusive right to develop prime editing for creating or correcting any single-base transition mutation, as well as for treating sickle cell disease.

Conclusions: BRAF mutation signature is highly associated with poor prognosis in colorectal cancer, especially in advanced stage, and the molecules associated with epithelial-mesenchymal transition ...

Recurrent point mutations that involve CG to TG transitions were identified in exon 18, exon 22 and exon 24, and a single CG to TG transition was identified in exon 23.

The medical view of cancer is in transition, as cancer doctors increasingly focus on the defective genes that are driving the disease rather than the organ in which it takes root.

EPFL scientists have shown that a gene linked to a rare childhood disease is essential for regenerating intestinal stem cells ...

Background: Mutations in p53 gene are observed in ∼50% of all human cancers. In breast cancer alone, 12%-32% of luminal, 84% of basal-like and 75% of HER-2 expressing tumors have apparent p53 ...