Osteoarthritis (OA) is the most common age-related joint disorder, affecting more than 500 million people worldwide and representing a leading cause of ...

Archaea represent a unique and ancient domain of life whose transcriptional regulation combines features of both bacterial and eukaryotic mechanisms. Unlike bacteria, many archaeal regulatory proteins ...

Cellular homeostasis and stress response are tightly coordinated processes involving a complex interplay between signaling ...

Nicotinamide adenine dinucleotide (NAD+) has long been conceptualized as a ubiquitous redox cofactor, embedded deeply within metabolic frameworks across living systems. More recent biochemical ...

This study is led by Professor XiaoqinLiu (Peking University Institute of Advanced Agricultural Sciences, Shandong Laboratory of Advanced Agriculture Sciences, Shangdong, China). The authors explored ...

In this valuable study, the authors develop new approaches to investigate mRNA imprinting, a phenomenon in which RNA-protein complexes form in the nucleus to influence the fate of transcripts in the ...

Using single-nucleus RNA sequencing, the authors map transcriptional changes in the rat ventral tegmental area following chronic inflammatory pain and acute morphine exposure. Notably, their ...