Pregame analysis and predictions of the Houston Astros vs. Minnesota Twins MLB game to be played on April 5, 2025 on ESPN.

Get Minnesota vs Houston baseball betting preview, spread and over/under insights for their matchup on April 5.

Its Thursday, April 3 and the Astros (2-4) are in Minnesota to open a series against the Twins (2-4). Hunter Brown is slated to take the mound for Houston against Joe Ryan for Minnesota. Houston yesterday wrapped up a dismal series against the San Francisco Giants with a 6-3 loss.

Joe Ryan, buzzkill. The Twins’ home opener was off to a rousing start on Thursday, Target Field alive with excitement over Matt Wallner’s leadoff triple, Byron Buxton’s can’t-catch-him infield hit and stolen base,

Christian Walker and Jeremy Peña homered and Brendan Rodgers had three hits and three RBIs to lead the Houston Astros to a 5-2 win over the Minnesota Twins.

Preview the April 3 matchup between the Minnesota Twins and Houston Astros with odds over/under, game spread, betting lines and more.

The Twins hope that a reverse travel schedule helps right-hander Bailey Ober (0-1, 27.00 ERA) find his footing after a rocky season debut. Ober was shelled for eight runs on eight hits in 2 2/3 innings in his first start on the road against the St. Louis Cardinals, and he will look to bounce back as he takes the mound in his home park.

The Twins-Astros game Thursday will be the third-earliest outdoor home opener for the Twins since 1961. The four earliest of their 35 outdoor home openers (not counting 2020, when COVID delayed the season opener until July) are: March 28,

Analyzing Thursday’s Houston Astros at Minnesota Twins odds and lines, with MLB expert picks, predictions and best bets.