A new study by EPFL researchers shows how RNA species called TERRA muster at the tip of chromosomes. [EPFL / Demcon-Nymus3D] Molecules that accumulate at the tips of chromosomes are known to play a ...

Shelterin, the complex consisting of telomere repeat–binding factor (TRF) 1, TRF2, repressor activator protein 1 (Rap1), TRF1 interactor 2 (TIN2), TINT1–PTOP–PIP1 (TPP1) and protection of telomeres 1 ...

A new study led by University of Pittsburgh and UPMC Hillman Cancer Center researchers shows that an enzyme called PARP1 is involved in repair of telomeres, the lengths of DNA that protect the tips of ...

Throughout a cell's life, corrective mechanisms act to repair DNA strand breaks. The exception is during the critical moment of cell division, when chromosomes are most vulnerable. Researchers found ...

A new study led by researchers at the University of Pittsburgh (Pitt) and UPMC Hillman Cancer Center has shown that an enzyme called PARP1 is involved in the repair of telomeres, the lengths of DNA ...

Our DNA is compacted and arranged into chromosomes, most of which are shaped like X’s. The ends of the chromosomes arms are ...

Our genome is organized into chromosomes, which are shaped like little X's. Every time a cell divides, the genome has to be replicated, and there are protective caps called telomeres on the ends of ...

Telomere is a repeated sequence (TTAGGG)N that caps the end of the chromosomes to protect them from damage during DNA replication prior to cell division. Telomere length is essential to the cell's ...

Chromosomal telomere repair treatment is near. Ultimately this could produce new ways to reverse aging in tissues and organs, and new treatments that may one day cure or even eradicate cancer. The ...

Today, your body will accumulate quadrillions of new injuries in your DNA. The constant onslaught of many forms of damage, some of which permanently mutates your genes, could initiate cancer and prove ...