MENLO PARK, Calif.--(BUSINESS WIRE)--Geron Corporation (Nasdaq:GERN) today announced the publication of preclinical data on TAT2, a small molecule telomerase activator. The studies show that human CD8 ...

Researchers have the molecular structure of telomerase. This should speed up the discovery of the best activators and inhibitors of telomerase. Good activators of telomerase has been shown to boost ...

Telomeres, posted at the edges of chromosomes, protect DNA from damage. The telomerase enzyme helps maintain the length and integrity of telomeres and acts as an aging regulator. Researchers have now ...

This new resource aims to change that by providing a detailed framework for understanding how different cancers maintain ...

Scientists discovered that the protein RPA plays a critical and previously unconfirmed role in stimulating telomerase to ...

A structural model of the telomerase enzyme shows how the binding domain (purple) tethers one end of the RNA component of the enzyme. (Image credit: Jansson et al., ) Researchers at UC Santa Cruz have ...

In the quest to unlock the secrets of aging and longevity, telomeres have emerged as key players. These protective caps at the ends of our chromosomes play a critical role in cellular aging. With each ...

Activation of telomerase, a dedicated reverse transcriptase that synthesizes telomeric sequences, is strongly associated with cancer, and recent observations confirm that telomeres and telomerase ...

Research has recently uncovered a crucial step in the telomerase enzyme catalytic cycle. This catalytic cycle determines the ability of the human telomerase enzyme to synthesize DNA. Research from the ...