A new study reveals how young synapses gradually mature to send chemical signals correctly — a process that can take days and depends on neural activity.
Endophilin A1 at postsynaptic sites promotes inhibitory postsynaptic organization through interaction with gephyrin to maintain E/I balance, which is essential for the suppression of epilepsy ...
A team of scientists from the University of Cologne's Institute of Biochemistry has made a decisive discovery about the molecular basis of synapse formation in the central nervous system. They studied ...
Representative cryo-electron microscopy image: a coloured image of the 3D structure of gephyrin, which was calculated from the data. A team of scientists from the University of Cologne’s Institute of ...
A team of scientists from the University of Cologne’s Institute of Biochemistry has discovered a significant finding about the molecular basis of synapse development in the central nervous system.
Tohoku University researchers have shown that Bergmann glial cells, astrocyte-like cells in the cerebellum, 'eat' their neighboring neuronal elements within healthy living brain tissue. Synapses - ...
In mice, data suggest that tau seeds sneak across synapses, spreading tangle pathology throughout the brain. Is the same true in people? Quite likely, say scientists led by Tara Spires-Jones, ...
Learning lots of new information as a baby requires a pool of ready-to-go, immature connections between nerve cells to form memories quickly. Called silent synapses, these connections are inactive ...
Scientists in Cologne offer a molecular perspective on the architecture of a synapse. They have discovered that a protein in the brain forms flexible filaments, thereby acting as an essential building ...