Researchers have developed a human intestinal cell model that closely mimics the structure and function of the human gut, enabling more precise prediction of drug-induced gastrointestinal toxicity ...
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Intestine-mimicking cell model accurately predicts drug toxicity
A cell model that replicates the structure and function of the human intestine has been developed, creating an evaluation platform capable of more accurately predicting adverse effects of new drugs.
Can the bend of a banana give us insight into cancer? What does the shape of a rice grain have to do with infertility? The ...
A team led by UT Southwestern Medical Center researchers has uncovered the atomic structure of a protein complex pivotal to the function of motile cilia, the hair-like structures extending from the ...
Biomolecular condensates were long believed to be simple liquid blobs inside cells. Researchers have now uncovered that some are actually supported by fine protein filaments forming an internal ...
Researchers from the University of Chicago (IL, USA) have reported that unstable, or ‘noisy’, chromatin enables cells to take on different roles in the body. This flexibility can support the immune ...
Tau proteins act like the brain's maintenance crew, helping maintain the structure and proper function of brain cells. In ...
Cryogenic microscopy at Diamond Light Source enables high-resolution, correlative imaging of cells under near-physiological ...
A proposed function of TADs is to contribute to gene regulation by promoting chromatin interactions within a TAD and by suppressing interactions between TADs. Here, we directly probe the ...
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