This study presents MPALM, a novel microscopy technique that captures nanoscale biomolecular dynamics, overcoming limitations ...

When single-molecule super-resolution microscopes were first commercialized some 15 years ago, they made headlines for their ability to resolve individual molecules and structures at the nanometer ...

News Medical talks to Samuel Penwell and Winfried Wiegraebe about how the Vutara VXL enables robust, high-throughput 3D super-resolution via single-molecule localization, pairing bi-plane detection ...

To unravel the complexities of biological phenomena, scientists have long relied on microscopy to visualize the intricate details of their specimens, including tissue architecture, cell morphology, ...

What does the inside of a cell really look like? In the past, standard microscopes were limited in how well they could answer this question. Now, researchers from the Universities of Göttingen and ...

Light field microscopy (LFM) is a revolutionary technique first introduced in 2006 which can essentially capture a 3D volume in a single snapshot, complete with digital refocusing and deconvolution.

Even those who maintain that super-resolution microscopy is a powerful tool of biological discovery have admitted that it may have a bit of an image problem. For example, in a recent review, several ...

How do photosynthetic organisms harvest light so efficiently? To help answer this question, researchers have developed an ultrafast transient absorption microscope with sensitivity approaching the ...

Super-resolution microscopy, such as SMLM, has changed the way scientists visualize cellular structures by breaking the diffraction limits of traditional light microscopy. By pinpointing the exact ...

One method for visualizing dynamic biological processes is single particle tracking, a localization microscopy method. For this technique to be successful, several factors need to be considered, ...