Scientists are aiming to determine the composition and topology of physiological Ashwell-Morell receptor ligands. Their findings will help uncover the receptor's still-hidden secrets. After earning ...

Glucagon-like peptide-1 (GLP-1) receptor agonists are incretin analogues that promote glucose-mediated insulin release and are used to treat type 2 diabetes mellitus and obesity. GLP-1 receptor ...

Details and references regarding individual diseases are provided in the Supplementary Appendix. CIDP denotes chronic inflammatory demyelinating polyneuropathy, Covid-19 coronavirus disease 2019, and ...

In a discovery that could guide the development of next-generation antidepressants and antipsychotic medications, researchers at the Icahn School of Medicine at Mount Sinai have developed new insights ...

Activation of the serotonin receptor, 5-HT1A, has been shown to regulate mood and cognition. The receptor is the primary target of buspirone, vilazodone, and gepirone, FDA-approved medications for the ...

Opioid receptors are fantastic targets for treating pain—but unfortunately, the drugs that target them can be addictive. Because the molecules suppress breathing and heart function, those drugs can ...

Fragmentation of Diagnostic Imaging Leading to a Management Error in a Patient With Small-Cell Lung Cancer Fig 2. Summary of guideline recommendations. AEs, adverse ...

New research from Texas A&M University suggests certain compounds in coffee may promote health by activating the NR4A1 receptor, which helps protect the body from stress and damage. The study ...

New drugs that spur weight loss and treat diabetes have been taking the public—and the pharmaceutical industry—by storm. The latest entrant, Zepbound, recently joined Ozempic, Wegovy, Victoza and ...