A research team has unveiled a breakthrough in understanding how specific genetic sequences, known as pseudogenes, evolve. Rice University's Peter Wolynes and his research team have unveiled a ...
A new platform combines rational protein design with continuous evolution to discover functional molecules more efficiently. In medicine and biotechnology, the ability to evolve proteins with new or ...
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AI-powered strategy streamlines protein engineering by integrating structural and evolutionary constraints
A team of researchers has developed a method that could transform the field of protein engineering. The new approach, called AI-informed Constraints for protein Engineering (AiCE), enables rapid and ...
The key insight with a new strategy for training protein engineering models, called EvoRank, is to harness the natural variations of millions of proteins generated by evolution over deep time and ...
The ability to evolve proteins with new or improved functions provides powerful applications for the development of selective, high-affinity antibodies, enzymes with new catalytic properties, and the ...
Proteins are life’s molecular workhorses, doing everything from turning sunlight into food to fighting viruses. They are built from 20 different types of amino acid molecules, so even a small protein ...
Protein engineering is a powerful biotechnological process that focuses on creating new enzymes or proteins and improving the functions of existing ones by manipulating their natural macromolecular ...
EvoRank offers a new and tangible example of how AI may help bring disruptive change to biomedical research and biotechnology more broadly. Using the MutRank framework trained with EvoRank, Danny Diaz ...
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