Four tiny 3D organs connected themselves in a lab dish, forming a replica of the human pain pathway, in a new study. The discovery allows scientists to better understand chronic pain and how pain ...

A breakthrough discovery reveals how the SLC45A4 gene fine-tunes polyamine transport in sensory neurons, reshaping our understanding of pain and opening new paths for targeted therapies. Study: ...

This new article publication from Acta Pharmaceutica Sinica B, discusses allosteric modulation of G protein-coupled receptors as a novel therapeutic strategy in neuropathic pain. Neuropathic pain is a ...

Researchers from the National University of Singapore (NUS), in collaboration with Peking University, China, have made a discovery regarding the TRPV1 (transient receptor potential vanilloid 1) ion ...

Scientists created a model of the human pain pathway in a dish by connecting four separate brain organoids. The feat should help them understand sensory disorders like those affecting pain perception.

It’s not all in your head, but your expectations can sway your perception of pain intensity. Information about expectations — the driver of the placebo effect — travels from the cortex to groups of ...