PHILADELPHIA, PA—For high-risk patients with heterozygous familial hypercholesterolemia (HeFH), a novel therapy that shuts off the PCSK9 gene can lower LDL cholesterol, early data from the heart-1 ...

Researchers report early but encouraging results on an experimental gene-editing treatment for high cholesterol.

NEW ORLEANS -- Innovations in lipid lowering get a major chance to shine, and potentially move the needle in cardiometabolic ...

An experimental gene-editing therapy developed by Crispr Therapeutics is showing promise for treating heart disease.

A revolutionary gene-silencing technique has shown that a single treatment can dramatically lower LDL cholesterol levels for over a year—without permanently altering DNA. Could this be the future of ...

For decades, statins like Lipitor and Zocor have been the cornerstone of cholesterol management. But as experts note, they don’t work for everyone — and now, a new wave of advanced therapies is ...

In patients with atherosclerosis and/or diabetes without a prior heart attack or stroke, evolocumab cut the risk for first ...

Researchers have developed a DNA-based therapy that targets the PCSK9 gene to lower cholesterol naturally. Using polypurine hairpins, they increased cholesterol uptake by cells and reduced ...

Because identical twins develop from a single fertilized egg, they have the same genome, the entire set of genetic material found in an organism. So, any differences between them, even in traits with ...

PHILADELPHIA -- A DNA base editing therapy, intended for lifelong lowering of LDL cholesterol, passed initial tests in people with severe, advanced atherosclerotic cardiovascular disease (ASCVD).

Eli Lilly and Company is acquiring Verve Therapeutics, Inc. for $1B upfront plus a $3/share CVR upon milestone being met, driven by promising gene-editing therapies for ASCVD. VERVE-102, a one-time IV ...

BOSTON, Oct. 31, 2023 (GLOBE NEWSWIRE) -- Verve Therapeutics, Inc., a clinical-stage biotechnology company pioneering a new approach to the care of cardiovascular disease with single-course gene ...