(A) Cryo-EM structure overview of HSV-1 gB in complex with D48 Fab. The side view and top view were presented. The HSV-1 gB trimer and D48 Fab VH/VL were colored differently. (B) Neutralization assay ...

Antibodies are immune proteins that our bodies produce to help fight off infection. Where they recognize and bind a pathogen — and how — can give important clues to the microbe’s vulnerabilities. Fred ...

An antibody cocktail generated in humanized mice protected hamsters from lethal doses of Nipah virus, offering a new ...

Antibiotic-resistant bacteria pose a major challenge to healthcare systems worldwide. Due to numerous resistance mechanisms, infections with the pathogen Pseudomonas aeruginosa are particularly feared ...

An international team has for the first time researched the longevity of neutralizing antibodies in HIV-1-infected people. Currently, it is assumed that an HIV-1 vaccine can only be effective if it ...

Drug conjugates (ADCs) developed at Institute of Science Tokyo combine a CD4 mimic with neutralizing antibodies for enhanced suppression of human immunodeficiency virus (HIV) infection. By targeting ...

“Our results show how different factors boost the formation of antibodies that broadly combat different viral strains. This will pave the way for us to systematically push ahead with the development ...

Broadly neutralizing antibodies (bNAbs) are among the most promising new treatments for HIV, offering the potential to forego traditional daily dose of antiretroviral drugs. In one recent clinical ...

Measles is a highly contagious, airborne disease that tends to strike children the hardest. Despite extensive vaccine efforts, the virus remains a major health threat. Scientists at the La Jolla ...

For years, researchers have been hoping for vaccines that protect people against not just one strain of HIV, but every strain of the quickly mutating virus.