Yale researchers have discovered how megakaryocytes — giant blood cells that produce wound-healing platelets — manage to grow 10 to 15 times larger than other blood cells. The findings, to be ...
Megakaryocytes are the parent cells that make platelets—sticky bodies that circulate in the bloodstream and help the blood to clot when you get cut. They are also the culprits that contribute to clot ...
Scientists from the Stowers Institute for Medical Research have discovered that megakaryocytes, best known for producing platelets that heal wounds, also play a critical role in regulating stem cells.
Mesenchymal stromal cells are key components of hematopoietic stem cell (HSC) niches in the bone marrow. Two studies now show that hematopoietic-derived megakaryocytes also contribute to the HSC niche ...
Adipocytes can be converted into mesenchymal stem cells, which can then be converted into megakaryocytes. These megakaryocytes can be used to produce platelets, which may be a source of safer platelet ...
Megakaryocytes (MKs), known for their role in platelet production, have emerged as critical players in immune responses, showcasing versatility in both physiological and pathological contexts. Recent ...
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Destabilizing microtubules to boost platelet production from iPS cell-derived megakaryocytes
A collaborative research team led by Dr. Thorsten Schlaeger (Boston Children's Hospital) Emiri Nakamura and Professor Koji Eto (Department of Clinical Application) has identified microtubule (MT) ...
Scientists found that megakaryocytes act as 'bouncers' and thus modulate bone marrow niche properties and cell migration dynamics. Hematopoiesis is the process of forming blood cells, which occurs ...
Our bodies still hold plenty of secrets, and scientists have just uncovered a doozy: the lungs play a key role in producing blood. Until now, this task was ascribed solely to bone marrow, but studies ...
The COVID mRNA vaccine generates enough of an antibody response to protect against severe disease for six months. But other vaccines offer years-long — even lifelong — immunity, as is the case with ...
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