Proteins in cells are highly flexible and often exist in multiple conformations, each with unique abilities to bind ligands. These conformations are regulated by the organism to control protein ...

Structural mass spectrometry has emerged as a powerful approach to elucidate the three‐dimensional conformations of proteins and their complexes under near‐physiological conditions. In particular, ...

Mass spectrometry has evolved into a cornerstone of structural proteomics, offering rapid, sensitive and site-specific insights into protein architecture, interactions and dynamics. By coupling ...

A new data-driven technique, called fingerprint mass spectrometry, provides a method for measuring the mass of individual proteins using nanoscale devices. Caltech scientists have developed a method ...

MALDI remains a powerful tool for analyzing large biomolecules with minimal fragmentation. In this process, peptides or proteins are co-crystallized with a matrix on a metal plate. A laser pulse ...

An interdisciplinary team led by Prof. Yao Zhongping, Associate Head and Professor of the Department of Applied Biology and Chemical Technology at The Hong Kong Polytechnic University, specialises in ...

Our food and our bodies are full of tiny protein fragments called peptides. These small chains of amino acids act as ...

Mass spectrometry is already a powerful tool for determining what kind and how many molecules are present in a given sample. But most instruments still analyze their molecules one or just a few at a ...

What are you really measuring in proteomics? As the field expands across discovery and translational research, understanding ...

Si Incorporated (Nasdaq: QSI) ("Quantum-Si," "QSI" or the "Company"), a proteomics company redefining protein analysis ...