Definition: Gene expression is the process by which a cell turns the information in a gene into a functional product, such as an RNA molecule or a protein. In simple terms: gene expression is how a ...

Fine-tuning a gene centrally involved in regulating the immune system offers potential clues for future autoimmunity and cancer treatments. The immune system faces a delicate balancing act: it must be ...

A schematic showing the cytosine base editing intermediate and the various outcomes that can occur when the UNG protein is active. You may have seen it in the news recently: a baby in Pennsylvania ...

The immune system faces a delicate balancing act: It must be aggressive enough to fight infections and cancer, yet restrained enough to avoid attacking the body's own tissues. More than two decades ...

Cell and gene therapy (CGT) has evolved from a niche research pursuit into a central force in biopharmaceutical innovation. By engineering living cells and genetic material to repair or replace faulty ...

A team of scientists—including Jenny Umhoefer, seen here—uncover potential clues for future autoimmunity and cancer treatments by learning to fine-tune a gene that is centrally involved in regulating ...