Scientists from the Université de Montréal and McGill University have re-engineered a human enzyme, a protein that accelerates chemical reactions within the human body, to become highly resistant to ...

Enzymes, nature's molecular architects, have been at the heart of industrial processes for decades. Today, the dynamic field of Enzyme Engineering and Modification is driving these biocatalysts ...

Sanofi has developed a simpler way to create site-specific antibody-to-mannose-6-phosphate (M6P) conjugates that eliminates the need for enzyme remodeling. This more straightforward method makes M6P ...

This method uses polymer modifications to tune enzyme activity for increased solubility in non-native solvents. Tuning the miscibility of enzymes in non-native solvent environments has important ...

A consortium of scientists has discovered new non-histone targets for one enzyme previously believed to modify only histones -- the group of proteins that creates tightly bundled packages of DNA ...

We have synthesized a hybrid subtilisin the solubility of which can be regulated by photoirradiation through coupling with a photoresponsive copolymer that carries spiropyran groups in its side chains ...

A seemingly subtle swap of metals—substituting a zinc ion with a cobalt ion—and a mutation ramps up the overall electric field strength at the active site of an enzyme, Stanford scientists find. The ...

One of these days, the ability of our cells and tissues to regenerate and repair themselves will come to a stop. Researchers hoping to better understand the processes that regulate aging are studying ...

The enzyme ALKBH1 can remove molecular modifications from transfer RNA, causing a measurable effect on protein translation in the cell, new research demonstrates. The study sheds new light on how ...

Now Health Group has received a Food and Drug Administration (FDA) letter of no objection that its enzyme-modified organic stevia ingredient is generally recognized as safe (GRAS), the company has ...

Covalent attachment of ubiquitin and SUMO to proteins plays a major role in regulating cellular functions. Both modifications depend on a similar enzymatic cascade. Ubiquitination involves a single E1 ...