New Cornell research is providing a fresh view into the ways a common chemotherapy agent, etoposide, stalls and poisons the essential enzymes that allow cancer cells to flourish. The findings, from ...
Andrés Aguilera's laboratory, in collaboration with that of Ralf Wellinger (both professors in the Department of Genetics at the University of Seville in CABIMER) and with PharmaMAR, has identified ...
New research is providing a fresh view into the ways a common chemotherapy agent, etoposide, stalls and poisons the essential enzymes that allow cancer cells to flourish. New Cornell research is ...
The solution to DNA's topological problems comes in the form of enzymes called topoisomerases that serve as "swivels" and allow the molecule to perform its requisite acrobatics. Type I topoisomerase ...
Researchers have uncovered the enzyme behind chromothripsis, a chaotic chromosome-shattering event seen in about one in four cancers. The enzyme, N4BP2, breaks apart DNA trapped in tiny cellular ...
A Dutch led international team of researchers has unravelled how nature releases the torque built up in DNA at the molecular level. The researchers from Delft University of Technology, the Ecole ...
Circulating tumor cells and tumor DNA in patients with resectable colorectal liver metastases: The MIRACLE. This is an ASCO Meeting Abstract from the 2024 ASCO Annual Meeting I. This abstract does not ...
A team of Penn State scientists has shed light on the processes that lead to certain human DNA mutations that are implicated in hundreds of inherited diseases such as tuberous sclerosis and ...
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