In autoimmune disorders, immune cells targeting "self" proteins are mistakenly activated, resulting in abnormal expansion and ...
A multidisciplinary team has used advanced imaging and computational modeling to analyze the "crosstalk" between neurons and their supporting glial cells in the human brain. This approach highlights ...
A team of researchers from the San Raffaele-Telethon Institute for Gene Therapy (SR-TIGET, Milan), led by Nadia Coltella and Luigi Naldini, has unveiled a powerful strategy to rejuvenate the ...
Cholangiocarcinoma (CCA) is a deadly cancer, characterized by abundant stroma. The tumor microenvironment (TME) plays an important role in its aggressive behavior and poor response to therapeutics; ...
Renal cell carcinoma (RCC) ranks among the top 10 most prevalent malignancies globally. The clear cell RCC (ccRCC) subtype originating in the proximal renal epithelial tubules accounts for ~75% of ...
COLUMBUS, Ohio – Research led by The Ohio State University Wexner Medical Center and College of Medicine explores the ways brain cells communicate, revealing fresh insight into the progression of ...
Left: UMAP projections of CD8⁺/WPRE⁺ (adoptive T cells) and CD8⁺/WPRE⁻ (endogenous T cells) cells mapped onto a reference TIL atlas reveal a reduced prevalence of exhausted CD8⁺ T cells and enrichment ...
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