Metal-mediated base pairing is an emerging paradigm in which metal ions replace or complement natural hydrogen bonds between nucleobases in DNA and RNA duplexes. By coordinating transition metals such ...

In the double helix structure of DNA, thymine forms a base pair with adenine through two hydrogen bonds. This specific pairing is known as complementary base pairing and is essential for the stability ...

This image illustrates the chemical structures of the five main nucleobases found in DNA and RNA. The pyrimidines, thymine (DNA), uracil (RNA), and cytosine are shown on top while the purines, adenine ...

There are plenty of unanswered questions about the origin of life on Earth. But the research community has largely reached consensus that one of the key steps was the emergence of an RNA molecule that ...