Both CBEs and ABEs have been extensively engineered to improve their efficiency, specificity, and targeting range, enabling a wide variety of base pair conversions across the genome. Base editing can ...

In a landscape where precision is paramount, the base editing market is emerging as a cornerstone of modern biotechnology, ...

Gene editing platforms like CRISPR-Cas9 that rely on nuclease activity introduce effective modifications, however, they arise from double strand DNA breaks (DSBs) introduced by the nuclease that can ...

While researchers have long appreciated the enormous potential of genome editing to treat disease, applications of these technologies in humans have historically been limited by safety concerns. Even ...

Verve Therapeutics said Sunday it has generated the first human proof-of-concept data for its in vivo base editing therapy VERVE-101—the first base editing treatment to reach the clinic—in patients ...