If you are anything like us, whenever you plan a journey, you spend a remarkable amount of time thinking about the start and ...

Entropic forces have been argued to drive bacterial chromosome segregation during replication. In many bacterial species, however, specifically evolved mechanisms, such as loop-extruding SMC complexes ...

Intracellular DNA can become damaged and/or distorted through a multitude of endogenous and exogenous sources (e.g., post-replication mismatches, base oxidation, cyclobutane pyrimidine dimers) 1,2.

When bacteria cells replicate, they do so a little differently than human cells do. They don't undergo mitosis, a splitting that involves construction of spindles to carefully separate the DNA after ...

Scientists have uncovered how DnaA, the master key to DNA replication, opens the door to bacterial growth. This breakthroughpaves the way for new antibiotics to combat the rising tide of antibiotic ...

Scientists assess bacterial growth trajectories to better predict infectious capacity and the conditions that aid proliferation. This article explores the key factors that influence bacterial ...

Top: Chromosome separate with functioning SMC in two models, line drawing and filled-space. The red and pink dots indicate, respectively, ori on each copy of DNA. Bottom: DNA separating without ...

Transposons are critical drivers of bacterial evolution that have been studied for many decades and have been the subject of Nobel Prize winning research. Now, researchers from Cornell University have ...

Red arrows indicate the DNA repair pathways that are known to aid bacterial survival as persisters and gamblers in the presence of fluoroquinolones. Blue color arrow indicates downregulation, while ...

Researchers showed that the way in which genes are turned on and off as bacteria grow provide clues to their regulation. Bacterial infections cause millions of deaths each year, with the global threat ...

The bacteria that cause tuberculosis (TB) may have an "on-off switch" that lets them pause and restart growth, according to a new study from the University of Surrey and the University of Oxford. The ...

In a breakthrough discovery, published in Nature Communications, scientists from Queen Mary University of London in collaboration with researchers at Newcastle University and The Francis Crick ...