I'm not sure about the specifics of the software you're talking about, but in general, going from 16-bit to 24-bit means you'd have a 16-bit recording being described by a 24-bit file, in short, it's ...

As part of the ADS1298 ECG/EEG AFE family, the 16-bit/1-ch ADS1191, 16-bit/2-ch ADS1192, 24-bit/1-ch ADS1291, 24-bit/2-ch ADS1292, and 24-bit/2-ch ADS1292R ECG and EEG AFEs are the first to offer 16- ...

I'm not talking about a reduction in color from 24 bit to 16 (plus another channel, I know). I'm talking about 16 bit luminance values such that color setting that would take advantage of a monitor ...